: Identifying structures on real human brains or histology slides.

The International Brain Bee is one of the most prestigious neuroscience competitions for high school students globally. However, the competitive landscape has shifted dramatically. If you are studying with outdated advice, old syllabi, or unpatched reading lists, you are preparing for an entirely different exam.

Modern bees love to ask about cutting-edge techniques. Ensure you know how CRISPR, optogenetics, fMRI, and EEG work fundamentally.

“A researcher uses two-photon calcium imaging to observe a dendritic spine in the CA1 region of the hippocampus. If the spine undergoes long-term potentiation (LTP), which of the following cascades is initiated first?” Answer: Glutamate binding to NMDA receptors -> Calcium influx -> CamKII activation. Difficulty: 8/10.