You can’t tank her hits, so don't try. Swap one defensive relic for a movement speed or dash-cooldown item.
: Because the boss counters every 7 hits, units with many multi-hit attacks (like giantess of abyss guide better
Focus on gear with high Abyssal Resistance . Light armor users should prioritize movement speed to dodge the sweeping melee attacks, while heavy armor users need to maintain high physical mitigation for her devastating slam attacks. Consumables: Greater Abyssal Oil: Increases damage against the Giantess. Elixir of Focus: Enhances stamina regeneration for dodging. You can’t tank her hits, so don't try
Once you have better runes, you can transition to teams that aim to kill the boss before it counters too often: Light armor users should prioritize movement speed to
Position your team in a "star" formation around her, ensuring Corruption Spread doesn't jump easily.